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Studies of combined treatments for reducing serum uric acid in patients with gout

goutSUA_CFBcomb.Rd

A dataset from a systematic review of interventions for lowering Serum Uric Acid (SUA) concentration in patients with gout (not published previously). The outcome is continuous, and aggregate data responses correspond to the mean change from baseline in SUA in mg/dL. Treatments with similar doses have been pooled together to improve network connectivity and facilitate evidence synthesis, resulting in 19 treatments of 7 agents included in the network. Standard deviations have been imputed for 181 observations.

Usage

goutSUA_CFBcomb

Format

A data frame with 224 rows and 7 variables:

  • studyID Study identifiers

  • time Numeric data indicating follow-up times

  • y Numeric data indicating the mean response for a given observation

  • se Numeric data indicating the standard error for a given observation

  • treatment Treatment identifiers as factors. Labels are shortened treatment names.

  • treatname Character data giving the full names of each treatment in the format agent_dose

  • class Shortened agent names stored as factors.

Source

Pfizer Ltd.

Details

goutSUA_CFBcomb is a data frame in long format (one row per observation, arm and study), with the variables studyID, time, y, se, treatment, treatname and class.